Medicine for acne image
Acne can be frustrating especially in teenagers. It causes disfigurement which may result in psychological disturbance. An effective medicine for acne would have a marvelous effect both physically and psychologically. Selection of a medicine for acne depends upon many factors: 1- Type of skin lesion: whiteheads, blackheads, papules, pustules, nodules and cysts. 2- Nature of skin: dry, oily or normal. 3- Severity of acne: mild, moderate or severe 4- Presence of inflammatory changes.
The goal of acne therapy is to get rid of existing lesions and prevent the formation of new ones. Most treatments resolve existing acne lesions and, with continuous use, discourage new ones from forming. Given the way acne occurs, acne treatments do one or more of the following: • Reduce sebum productionReduce P. acnesNormalize the shedding of skin cells. Two or more acne products are often used to treat different acne causes The most effective acne medicines are available only by physician prescription. As with any potent pharmaceutical agent, they should be used only after examination by a physician and under the supervision of a physician. Prescribed medications include antibiotics, topical retinoids, anti-androgen spironolactone; and oral isotretinoin for treatment of severe nodular acne and acne resistant to other medications. According to mechanism of action, Medicines for acne include: 1- Cleansing agents 2- Exfoliating agents 3- Antibiotics 4- Keratin life cycle modifiers 5- Sebum production controllers 6- Moisturizing agents An ideal medicine for acne should be: Effective, not expensive and has minimal or no side effects. In order to prevent disfiguring complications of acne such as scarring and pigmentation, you should consult a dermatologist especially in severe cases.

Friday, May 23, 2008

medicine for acne logoMedicine for acne: Oral contraceptives

Oral contraceptives.
Ovarian hypersecretion of androgens can be suppressed with oral contraceptives. Most oral contraceptives contain combinations of estrogens and progestational agents. Oral contraceptives with estrogen (ethynyl estradiol or mestranol) and progestins of low androgenic activity are the most useful. Higher dose estrogen pills are more effective but not as safe.
Most synthetic progesterones have some degree of androgenic activity, which is undesirable in patients who already have signs of androgen excess. Oral contraceptives that appear to be useful in androgenic disorders and acne include Demulen, Ovcon 35, Modicon, Brevicon, and Ortho-Novum 7/7/7. The progesterone ethynodiol diacetate in Demulen is a relatively low androgenic progesterone. Norethindrone is more androgenic, but the low doses contained in Ovcon-35, Modicon, and Brevicon make these pills relatively nonandrogenic. Triphasil, containing levonorgestrel, and Diane (available outside the United States), containing cyproterone acetate, produced a 72% reduction in acne.
The estrogenic and androgenic activity of various oral contraceptives are listed in the Formulary. In many instances acne flares after the use of oral contraceptives is discontinued. Selection of an appropriate agent may provide the benefit of effective acne therapy for women who have chosen an oral contraceptive for birth control. Women in their thirties and forties without risk factors such as smoking or a family history of premature cardiovascular disease can safely use low-dose oral contraceptives to reduce ovarian androgen secretion.
Drugs that may reduce the effectiveness of oral contraceptives
Antibiotics
ampicillin, amoxicillin, isoniazid, metronidazole, penicillin, rifampin, tetracycline
Anticonvulsant drugs
barbiturates, carbamazepine, ethosuximide, phenytoin, primidone
Sedatives and hypnotics
barbiturates, benzodiazepines, chloral hydrate
Others
antacids, antimigraine preparations, clofibrate

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